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Sovalimus is manufactured by Ha Tinh Pharmaceutical Joint Stock Company - VIETNAM. Sovalimus 0.03 has the main ingredient is Tacrolimus used in the treatment of dermatitis, eczema, itching, ... Sovalimus can be used for long-term treatment but not for continuous use.
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1. What is Sovalimus 0.03?
Sovalimus 0.03 is a prescription drug, classified as an immunosuppressant. Sovalimus contains tacrolimus as the active ingredient.
Dosage form: skin ointment Packing form: each tube contains 3g tacrolimus and excipients just enough 10g.
Pharmacodynamics: Tacrolimus, extracted from Streptomyces tsukubaensis, has immunosuppressive effects, but the exact mechanism is unknown. In addition, tacrolimus also has antibacterial properties but is limited. In patients with atopic dermatitis, the healing effect of tacrolimus was associated with a decrease in the Fc receptor in Langerhans cells, as well as a decrease in T-lymphocyte stimulation. Tacrolimus did not affect synthesis. collagen synthesis.
Absorption: Data from human volunteers indicate that tacrolimus has little or no systemic effects with single or repeated topical application. The bioavailability of tacrolimus is less than thở 0.5%. The majority of patients with atopic dermatitis treated with single or repeated doses of Sovalimus had plasma concentrations less than thở 1 ng/ml. At present, there is no evidence of tacrolimus accumulation in patients on prolonged therapy. Distribution: When applied topically, tacrolimus acts selectively on the skin and has a very low systemic effect. Tacrolimus is bound lớn plasma proteins at a high rate (98.8%). Metabolism: When applied topically, no metabolism of tacrolimus was detected. A very small amount of tacrolimus is absorbed into the systemic circulation and is metabolised in the liver and gastrointestinal tract by the oxidase enzyme system. Elimination: The clearance of tacrolimus is reduced in patients with severe hepatic impairment. At repeated dosing, the half-life of tacrolimus is 65 hours in children and 75 hours in adults.
3. Indications and contraindications of the drug Sovalimus
Sovalimus 0.03 is intended for use in adults and children over 2 years of age. Accordingly, the drug is indicated in the following cases:
Atopic dermatitis in patients who have failed previous therapies. Eczema in adults. Contraindications: Absolutely bởi not use Sovalimus for the following subjects:
Patients who are allergic lớn any of the ingredients of Sovalimus Children under 2 years of age Have Netherton syndrome that increases drug absorption
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4. Dosage and how lớn use Sovalimus 0.03
Sovalimus 0.03 is a prescription drug, so sánh you can only use it when prescribed by your doctor. Patients should absolutely follow the doctor's instructions about the dose and method of taking the drug. In addition, bởi not arbitrarily change the dose and route of medication as well as give the medicine lớn others, even if they have the same disease as you.
Dosage: apply 2 times / day. After the symptoms are gone, bởi not stop the drug immediately, but continue lớn maintain it for another week.
How lớn apply the medicine:
Wash the damaged skin before applying the medicine. Sovalimus is for topical use, not for oral use. Do not bandage the injured area after applying the medicine. Apply a thin layer on the affected skin, gently mas sa lớn absorb the medicine. What lớn bởi if you miss a dose?
Apply the medicine as soon as you remember, bởi not apply double the amount lớn làm đẹp for the missed dose. What lớn bởi in case of an overdose?
Taking Sovalimus 0.03 may increase the chance of side effects. When you miss taking Sovalimus, you should immediately go lớn the nearest medical facility for timely monitoring and treatment.
5. Side effects when using Sovalimus
During the use of Sovalimus, you may encounter the following undesirable effects:
Common: hair loss, visual disturbances, ear pain, photosensitivity, increased liver enzymes, increased blood bilirubin , increased creatinine, dysglycemia, anaphylaxis, edema, arrhythmia, chest pain, dyspnea, hypertension, leukocytosis, leukopenia, anorexia, constipation, gastritis, loss of taste , anxiety, depression, dizziness, sweating, dizziness, migraine, chills, joint pain, neuritis, subcutaneous hemorrhage, nosebleed, hypoxemia, dehydration, .. Uncommon: fever, allergy, erythema, skin burning sensation, itching, eczema, tương tác dermatitis, asthma, pharyngitis, ... The side effects listed above are not exhaustive. You may experience other unusual symptoms during the use of Sovalimus. Therefore, immediately tương tác your doctor or pharmacist as soon as there is an abnormality for timely advice and guidance.
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6. Sovalimus drug interactions
Drug interactions can change the absorption and effects of drugs. Therefore, lớn ensure safety, please list your current medications, including prescription drugs, over-the-counter drugs, functional foods, vitamins, ... for advice on possible drug interactions. may happen.
7. Some notes when using Sovalimus
Pregnancy and breast-feeding: There are insufficient data on the safety and efficacy of this drug treatment in pregnant women as well as nursing mothers. Therefore, it is necessary lớn consult a doctor when deciding lớn take the drug. Driving and operating machines: There are no data on the effect of Sovalimus on this subject, so sánh it should be used with caution. In patients with dermatitis caused by Eczema herpeticum, Sovalimus increases the risk of infection with Varicella zoster virus, Herpes simplex . Caution should be exercised when using the drug in organ transplant patients due lớn the possibility of lymphoma development. Limit exposure lớn light. Safety and efficacy have not been established in patients with erythema nodosum. Store Sovalimus medicine in sealed packaging, in a dry place, away from moisture and direct light. A good storage temperature for the drug is below 30 degrees Celsius. Keep Sovalimus out of reach of children and pets.
Sovalimus is manufactured by Ha Tinh Pharmaceutical Joint Stock Company - VIETNAM. Sovalimus 0.03 has the main ingredient Tacrolimus used in the treatment of dermatitis, eczema, itching. To ensure effective treatment and avoid unwanted side effects, patients need lớn follow the doctor's instructions exactly , specialist pharmacist.
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