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Gensonmax medicine is made in the sườn of a topical cream, the package includes a box of 1 tube of 10g. The drug is indicated for the treatment of dermatological diseases with good results. To ensure effective use and avoid unwanted side effects, patients need vĩ đại strictly follow the instructions of the doctor.

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1. What is Gensonmax? The effect of the drug Gensonmax

1.1. What is Gensonmax topical? Gensonmax topical is a topical medication used vĩ đại treat symptoms of dermatological diseases such as tương tác dermatitis, insect stings or dermatitis caused by secondary bacterial infections.
Ingredients for a tube of Gensonmax 10g topical include:
Clotrimazol: 0.1 g; Gentamicin (as Gentamicin sulfate): 0.01 grams; Betamethasone dipropionate: 0.0064 grams; Other excipients in sufficient quantities. The dosage sườn of the drug Gensonmax is: Skin cream.
1.2. The effect of Gensonmax topical cream Gensonmax topical cream is a combination of 3 active ingredients with synergistic effects. Clotrimazol is a fungicide, Gentamicin is an antibiotic belonging vĩ đại the group with bactericidal effects and Betamethasone dipropionate is a synthetic corticosteroid with anti-inflammatory and anti-allergic effects. Specific effects for each active ingredient are as follows:
Clotrimazol is a broad-spectrum antifungal drug of the azole group, due vĩ đại its low absorption capacity, it mainly treats fungal infections of the skin, mucous membranes and vaginal candidiasis. All azole antifungals are capable of inhibiting the alpha demethylase enzyme, which prevents the synthesis of ergosterol and lipids of the fungal cell membrane, changes the permeability of the cell membrane, thereby destroying fungal cells. Gentamicin is an aminoglycoside antibiotic that is active mainly on gram-negative aerobic bacteria and some specific gram-positive bacteria such as staphylococcus, streptococcus, pneumococcus. Drugs for the treatment of serious infections caused by gram-negative bacteria acquired in the hospital such as bacteremia, biliary tract infections, pneumonia, urinary tract infections. Besides, Gentamicin antibiotic is also effective against some bacteria such as Mycoplasma, Actinomyes. Mycobacterium, fungi and anaerobic bacteria with anti-Gentamicin activity. Betamethasone is a corticosteroid with strong glucocorticoid effects, and also has anti-inflammatory, anti-allergic, vasoconstrictor, rheumatic, lupus, multiple sclerosis, problems caused by low levels of adrenal hormones. Betamethasone can suppress the inflammatory response but cannot cure it completely. When you stop using the drug can cause the disease vĩ đại come back. Corticosteroids have the ability vĩ đại suppress the immune system, which can lead vĩ đại increased rates of infection and reduced effectiveness of vaccines and antibiotics. Long-term use of Betamethasone can cause osteoporosis leading vĩ đại fractures, adrenal gland shrinkage or atrophy leading vĩ đại some unwanted side effects vĩ đại health such as nausea or vomiting. 1.3. The pharmacokinetics of Gensonmax topical Clotrimazole is relatively low when applied topically. After topical application, the drug is distributed into the stratum corneum, the lower layer of the skin. Clotrimazoles are absorbed after metabolism, excreted mainly in the bile, excreted in the feces and urine. The mean half-life is between 3.5 and 5 hours. Gentamicin antibiotics lượt thích other aminosides, gentamicin is less absorbed from the gastrointestinal tract but well absorbed through intravenous and intramuscular injection. The drug can reach its maximum concentration 30 vĩ đại 60 minutes after intramuscular injection. Gentamicin is absorbed mainly in the extracellular fluid and has relatively little metabolism in vivo. In addition, the active substance Gentamicin is eliminated mainly via the urinary tract, with an average half-life of 2 vĩ đại 4 hours. Betamethasone is readily absorbed when applied directly vĩ đại the skin, and is less widely bound vĩ đại plasma proteins. The drug is metabolized mainly by the liver, partly in the kidneys and excreted from the body toàn thân in the urine.

2. Indications of the drug Gensonmax

Gensonmax topical is used topically vĩ đại treat the following pathological symptoms:
Atopic dermatitis, atopic eczema, also known as eczema, seborrheic dermatitis, ichthyosis, tương tác dermatitis , anal itching, vaginal itching, ... Some dermatophytosis skin diseases such as ringworm, ringworm, stem fungus, nail fungus, trichophyton fungus,... Suspected infection caused by bacteria secondary. Prevents infection from insect stings or minor burns on the skin.

3. Usage and dosage of the drug Gensonmax

3.1. Dosage of Gensonmax You can apply a layer of Gensonmax cream just enough on the affected skin area in each time, 2-3 times a day. For the best effect of the medicine, you should apply it regularly.
3.2. How vĩ đại use Gensonmax Before applying Gensonmax you need vĩ đại wash your hands and the area vĩ đại be applied. Take an appropriate amount of cream and rub it evenly on the damaged skin and surrounding areas, making sure vĩ đại cover the areas evenly. Do not apply too strong medicine that can negatively affect the skin, facilitate dermatitis, bacterial infection vĩ đại progress worse. Wash your hands after using Gensonmax topical, unless you are treating a skin infection. Keep the affected area clean and kiểm tra it regularly. The duration of the treatment depends on the patient's medical condition, the damaged skin, and the extent of the damage. If after about 4 weeks of use, you don't see any effect, you need vĩ đại review and maybe change vĩ đại another drug when prescribed by the treating doctor.
3.3. In case of overdose/forgotten dose In case of overdose: The composition of Gensonmax topical contains corticosteroids, so sánh when using the drug in overdose, symptoms of corticosteroid overdose include: increased appetite, calcium mobilization. and phosphorus associated with osteoporosis, nitrogen loss, tissue-reducing effect, hyperglycemia, increased susceptibility vĩ đại infection, adrenal insufficiency, increased adrenal cortex activity, mental and neurological disorders, muscle weakness. In case of acute overdose, the doctor will prescribe monitoring of serum and urine electrolytes, paying special attention vĩ đại the balance of sodium and potassium. In case of chronic toxicity, stop using the drug slowly, treat electrolyte imbalance if necessary. Because the cause of drug overdose has no specific antidote, gentamicin overdose or toxic reactions are symptomatic and supportive. If you forget vĩ đại take a dose, take it again as soon as you remember. If you remember when it's almost time for your next dose, skip it and stick vĩ đại your usual dosing schedule. You should not apply twice the amount of medicine.

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4. Undesirable effects of the drug Gensonmax

Some unusual manifestations may occur such as itching, redness, burning, irritation, erythema, urticaria, peeling, blistering, generalized allergy or anaphylactic reaction,. .. It is necessary vĩ đại pay attention vĩ đại the dose used because if the drug is used in large doses for a long time, it can cause unwanted side effects similar vĩ đại when using systemic corticosteroids. If the drug is used on a large scale, there is a pressure bandage that can cause skin irritation, dermatitis, hypopigmentation, rash, acne, ... The above are just some unwanted effects when using the drug, so sánh the Side effects may be incomplete. You need vĩ đại pay attention when using, if there are any other abnormal health symptoms, please consult the treating doctor.

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5. Gensonmax drug interactions

Topical drugs containing ingredients: Calcium, sulfafurazol, heparin, sulfacetamide, magnesium, acetylcysteine, chloramphenicol, actinomycin, doxorubicin, clindamycin reduce the effect of Gensonmax topical (caused by decreased activity of gentamicin). .
Use of Gensonmax topical with neuroleptics may cause muscle relaxation. In addition, the drug should not be used with some nephrotoxic drugs, because it may increase nephrotoxicity. Co-administration of an aminoglycoside such as Gentamicin with a beta lactam may increase bactericidal activity, and is usually indicated in patients with severe disease or impaired resistance.
Contraindicated vĩ đại use drugs containing gentamicin in people with kidney damage, hearing or allergy vĩ đại the drug. Gentamicin antibiotics for people with meningitis will not work because the bacteria are in a "resting" state. Betamethasone is a corticosteroid, which works vĩ đại soothe inflamed areas of the body toàn thân, reducing swelling, redness, itching, and allergic reactions. It is not recommended vĩ đại use this medicine while being treated with some drugs such as Desmopressin, Rilpivirine, Aceclofenac, Fluvoxamine, Ofloxacin, Piroxicam, Hydrocodone, Ibuprofen, Phenobarbital, Phenylbutazone ... or some vaccines such as Adenovirus vaccine, chickenpox vaccine, Varicella virus vaccine, ...
If you use Gensonmax topical for a long time, you may need vĩ đại monitor your diet, calories or add more protein vĩ đại your diet, diet potassium-rich diet. Besides, the treating doctor may ask you vĩ đại have an ophthalmology examination in necessary cases.
In addition, the active ingredient Gensonmax can also interact with foods, alcohol, and tobacco.

6. Some notes when using Gensonmax drug

Before using Gensonmax topical, you need vĩ đại carefully consult the instructions of the treating doctor, carefully read the instructions for use and refer vĩ đại the information below.
6.1. Contraindications of Gensonmax topical Gensonmax topical is contraindicated in the following cases:
Not used for people who are sensitive vĩ đại one of the ingredients of the drug. Do not apply the medicine on broken skin, extensive damage or closed wounds, especially in children and infants. Do not use the drug in the following cases: Tuberculosis, herpes simplex, shingles, eczema due vĩ đại them chickenpox, syphilis. Do not use in ophthalmology. 6.2. Precautions when using Gensonmax topical The lowest possible dose of corticosteroids should be used vĩ đại control the disease under treatment when the dose is reduced, tapering gradually. Do not use in the treatment of systemic fungi. Inform the treating physician if irritation occurs in the application area. Prolonged use of topical antibiotics can facilitate the rapid growth of non-susceptible pathogens such as fungi. Since Gensonmax topical contains Gentamicin, caution should be exercised regarding the risk of cross-allergenicity between aminoglycoside antibiotics. For children:
Children may have more obvious manifestations of adrenal insufficiency, which is caused by the use of corticosteroids, than thở adults. This is due vĩ đại the greater ratio of the damaged skin surface vĩ đại the weight of the whole body toàn thân. Children may experience signs of Cushing's syndrome, growth retardation, weight gain and increased intracranial pressure have been reported in children receiving topical corticosteroids. Manifestations of adrenal insufficiency in children include low plasma cortisol levels and unresponsiveness vĩ đại ACTH stimulation. Clinical manifestations of raised intracranial pressure include fontanelle bulge, headache, and bilateral papilledema. Other notes:
For the ability vĩ đại drive and use machines: The drug is suitable for driving and operating machines. Pregnancy: When using corticosteroids during pregnancy or in a person of childbearing potential, it is necessary vĩ đại follow the instructions of the treating physician after weighing the benefits and risks of the drug vĩ đại the mother and embryo or fetus. Lactation: Gensonmax topical is excreted in breast milk and may be harmful vĩ đại infants, as it may inhibit growth and cause other adverse effects such as hypoadrenalism. The benefit vĩ đại the mother must be weighed against the potential harm vĩ đại the infant. Gensonmax medicine is prepared in the sườn of a cream for topical application, packaging includes a box of 1 tube of 10g. The drug is indicated for the treatment of dermatological diseases with good results. To ensure effective use and avoid unwanted side effects, patients need vĩ đại strictly follow the instructions of the doctor.
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